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Details : C10RMP8 - NIST method for antiepileptic drugs (topiramate)
| Type (acronym) | rmp |
|---|---|
| Type | reference measurement procedure |
| Unique Nomination Number | C10RMP8 |
| Analyte Name | topiramate |
| IUPAC IFCC Number | CAS97240-79-4 |
| Method capable of Traceability of Analyte to SI or Defined Procedure | SI |
| Applicable Matrices | human serum |
| Name | NIST method for antiepileptic drugs (topiramate) |
| Organization that developed Validated Method | NIST |
| Measurement Techniques Used | ID-LC-MS/MS |
| Quantity | Mass fraction |
| From (0) | 6.86 |
| To (0) | 19 |
| Unit (0) | µg/g |
| From (1) | 0.159 |
| To (1) | 0.437 |
| Unit (1) | µg/g |
| Level of Confidence (%) | 95% |
| Peer Reviewed Publication | Development and validation of a reference measurement procedure for certification of phenytoin, phenobarbital, lamotrigine, and topiramate in human serum using isotope dilution liquid chromatography tandem mass spectrometry, Tai S et al., Anal. Bioanal. Chem., 2011, 40, 1915 |
| Review Team Name | drugs |
| Analyte Category Name | Drugs |
| Measurement principle/technique | Isotope dilution mass spectrometry |