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Details : C10RMP9 - NCCL ID-LC/MS/MS Reference procedure for serum Cholesterol
| Type (acronym) | rmp |
|---|---|
| Type | reference measurement procedure |
| Unique Nomination Number | C10RMP9 |
| Analyte Name | total cholesterol |
| IUPAC IFCC Number | CAS57-88-5 |
| Method capable of Traceability of Analyte to SI or Defined Procedure | SI |
| Applicable Matrices | lyophilized, fresh, or frozen human serum |
| Name | NCCL ID-LC/MS/MS Reference procedure for serum Cholesterol |
| Organization that developed Validated Method | Beijing Hospital Institute of Geriatrics and National Center for Clinical Laboratories(NCCL) |
| Measurement Techniques Used | ID-LC/MS/MS |
| Comments 1 | Oxidized to cholest-4-en-3,6-diones with chromic acid |
| Comments 2 | Calibration with NIM(National Institute of Metrology P. R. China)CRM GBW09203b Cholesterol |
| Quantity | Amount-of-substance concentration |
| From (0) | 1.29 |
| To (0) | 10.34 |
| Unit (0) | mmol/L |
| From (1) | 0.3 |
| To (1) | 1 |
| Unit (1) | % |
| Level of Confidence (%) | 95% |
| Peer Reviewed Publication | Serum cholesterol measured by isotope dilution liquid chromatography tandem mass spectrometry, Chen W et al., Clin. Chem. Lab. Med., 2011, 49(4), 669-676. |
| Review Team Name | metabolites and substrates |
| Analyte Category Name | Metabolites and substrates |
| Non-CCQM Key Comparison Report | IFCC External Quality assessment scheme for Reference Laboratories in Laboratory Medicine (RELA) |
| Non-CCQM Key Comparison Report Hyperlink | http://www.dgkl-rfb.de:81/ |
| Non-CCQM Key Comparison Report | Labcode: 18
|
| Non-CCQM Key Comparison Report | Results for year 2006, 2007, 2009, and 2012
|
| Measurement principle/technique | Isotope dilution mass spectrometry |