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JCTLM Database: higher-order reference materials, methods and services
Details : C11RMS13 - digitoxin in Blood serum, Blood plasma
| Type (acronym) | rms |
|---|---|
| Type | reference measurement service |
| Unique Nomination Number | C11RMS13 |
| Reference Laboratory Status | EQAS Organizer |
| Analyte Name | digitoxin |
| IUPAC IFCC Number | CAS71-63-6 |
| Applicable Matrices | fresh, frozen or lyophilized blood serum or plasma |
| Traceable to SI | Yes |
| Principle of Analytical Procedure | LC-ID/MS |
| Reference Method Listed in JCTLM | Yes |
| Name of JCTLM Listed Reference Method Procedure | INSTAND reference measurement procedure for digitoxin |
| JCTLM Database Identifier Number | C4RMP4 |
| Procedure Difference in Your Laboratory | No |
| Quantity | Amount-of-substance concentration |
| From (0) | 1 |
| To (0) | 100 |
| Unit (0) | nmol/L |
| From (1) | 2.5 |
| To (1) | 2.5 |
| Unit (1) | % |
| Level of Confidence (%) | 95% |
| Comments on Uncertainty Range | The stated expanded uncertainty value corresponds to the best measurement capability. |
| Reference Procedure Status Acceptable | Yes |
| Laboratory Status | b |
| Survey Organisation | IFCC RELA Surveys |
| Intercomparison Results Publicly Available | Yes |
| Link to Comparison Results | RELA - IFCC External Quality assessment scheme for Reference Laboratories in Laboratory Medicine at AND http://www.dgkl-rfb.de:81/index.shtml |
| Participation Status in Intercomparison Surveys acceptable | yes |
| Comments of Review Teams | The laboratory has met the requirements outlined in JCTLM WG2-P-03-B for this analyte. Note: The laboratory uses Digitoxin D5878 with =92% purity as a reference material for calibration. How does the laboratory verify the exact content of digitoxin? (reported best measurement capability is 2.5%). Using material with higher purity may be more appropriate. In reply to this, the laboratory has communicated, that in future a Cerilliant RM with 0.5% uncertainty will be used. |
| Recommended for Publication in the JCTLM List | Yes |
| Organization Acronym | INSTAND e. V. |
| Organization Name | Society for Promoting Quality Assurance in Medical Laboratories |
| Organization Website | http://www.instand-ev.de |
| Organization Country ISO Code | DE |
| Organization Country Name | Germany |
| Analyte Category Name | Drugs |