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Details : C12 RMP4R - CDC ID LC-MS/MS reference measurement procedure for total 17beta-estradiol

Type (acronym)rmp
Typereference measurement procedure
Unique Nomination NumberC12 RMP4R
Analyte Name17β-estradiol (total)
IUPAC IFCC NumberCAS50-28-2
Method capable of Traceability of Analyte to SI or Defined ProcedureSI
Applicable Matriceslyophilized, fresh, or frozen human serum
NameCDC ID LC-MS/MS reference measurement procedure for total 17beta-estradiol
Organization that developed Validated MethodCDC (Centers for Control and Prevention)
Measurement Techniques UsedID LC-MS/MS
Comments 1Calibrated with NMIJ- CRM 6004a
QuantityAmount-of-substance concentration
From (0)2.61
To (0)3670
Unit (0)pmol/L
From (1)4
To (1)4.8
Unit (1)%
Level of Confidence (%)95%
Peer Reviewed PublicationEvaluation of an isotope dilution HPLC tandem mass spectrometry candidate reference measurement procedure for total 17-β estradiol in human serum, Botelho J.C. et al., Analytical Chemistry, 2016, 88(22), 11123-11129
Analyte Category NameNon-peptide hormones
Measurement principle/techniqueIsotope dilution mass spectrometry