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Details : C15RMP7 - HSA ID/LC/MS/MS reference measurement procedure for urea in human serum
| Type (acronym) | rmp |
|---|---|
| Type | reference measurement procedure |
| Unique Nomination Number | C15RMP7 |
| Analyte Name | urea |
| IUPAC IFCC Number | CAS57-13-6 |
| Method capable of Traceability of Analyte to SI or Defined Procedure | SI |
| Applicable Matrices | human serum |
| Name | HSA ID/LC/MS/MS reference measurement procedure for urea in human serum |
| Organization that developed Validated Method | Health Sciences Authority (Singapore) |
| Measurement Techniques Used | Liquid chromatography-isotope dilution tandem mass spectrometry |
| Quantity | Amount-of-substance content |
| From (0) | 3 |
| To (0) | 20 |
| Unit (0) | mmol/l |
| From (1) | 0.06 |
| To (1) | 0.48 |
| Unit (1) | mmol/l |
| Level of Confidence (%) | 95% |
| Peer Reviewed Publication | Liquid chromatography isotope dilution tandem mass spectrometry method for the measurement of urea in human serum and assignment of reference values to external quality assessment samples, Yong S. et al, International Journal of Mass Spectrometry. 2017, 414, 87-93 |
| Analyte Category Name | Metabolites and substrates |
| CCQM Key Comparison Report | CCQM-K109, High polarity analytes in biological matrix: determination of urea and uric acid in human serum |
| CCQM Key Comparison Report Hyperlink | https://www.bipm.org/kcdb/comparison?id=1488 |
| Measurement principle/technique | Isotope dilution mass spectrometry |
| Measurement principle/technique | Liquid chromatography mass spectrometry |