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Details : C16RMP7R - ID LC-MS/MS reference measurement method for cyclosporine A in human whole blood
| Type (acronym) | rmp |
|---|---|
| Type | reference measurement procedure |
| Unique Nomination Number | C16RMP7R |
| Analyte Name | cyclosporin A |
| IUPAC IFCC Number | CAS59865-13-3 |
| Method capable of Traceability of Analyte to SI or Defined Procedure | SI |
| Applicable Matrices | frozen human whole blood;(EDTA, CDT) |
| Name | ID LC-MS/MS reference measurement method for cyclosporine A in human whole blood |
| Organization that developed Validated Method | Roche Diagnostics GmbH in collaboration with Institute of Laboratory Medicine, Hospital of the Ludwig-Maximilians University, and Labormedizinisches Zentrum Dr Risch Anstalt |
| Measurement Techniques Used | isotope dilution mass spectrometry |
| Comments 1 | tacrolimus, sirolimus and everolimus were quantified within the same mehod |
| Quantity | Mass concentration |
| From (0) | 5 |
| To (0) | 2100 |
| Unit (0) | ng/mL |
| From (1) | 5.5 |
| To (1) | 7.2 |
| Unit (1) | % |
| Level of Confidence (%) | 95% |
| Peer Reviewed Publication | An isotope dilution LC-MS/MS based candidate reference method for the quantification of cyclosporine A, tacrolimus, sirolimus and everolimus in human whole blood, Taibon J. et al., |
| Comments to be published via JCTLM DB | This reference measurement method was developed and validated by Roche Diagnostics GmbH in collaboration with the Institute of Laboratory Medicine, Hospital of the Ludwig-Maximilians University, and Labormedizinisches Zentrum |
| Analyte Category Name | Drugs |
| Measurement principle/technique | Isotope dilution mass spectrometry |