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Details : C16RMP8R - ID LC-MS/MS reference measurement method for everolimus in human whole blood
| Type (acronym) | rmp |
|---|---|
| Type | reference measurement procedure |
| Unique Nomination Number | C16RMP8R |
| Analyte Name | everolimus |
| IUPAC IFCC Number | CAS159351-69-6 |
| Method capable of Traceability of Analyte to SI or Defined Procedure | SI |
| Applicable Matrices | frozen human whole blood;(EDTA, CDT) |
| Name | ID LC-MS/MS reference measurement method for everolimus in human whole blood |
| Organization that developed Validated Method | Roche Diagnostics GmbH in collaboration with Institute of Laboratory Medicine, Hospital of the Ludwig-Maximilians University, and Labormedizinisches Zentrum Dr Risch Anstalt |
| Measurement Techniques Used | isotope dilution mass spectrometry |
| Comments 1 | cyclosporine A, sirolimus and tacrolimus were quantified within the same mehod |
| Quantity | Mass concentration |
| From (0) | 0.25 |
| To (0) | 50 |
| Unit (0) | ng/mL |
| From (1) | 4.7 |
| To (1) | 8.9 |
| Unit (1) | % |
| Level of Confidence (%) | 95% |
| Peer Reviewed Publication | An isotope dilution LC-MS/MS based candidate reference method for the quantification of cyclosporine A, tacrolimus, sirolimus and everolimus in human whole blood, Taibon J. et al., |
| Comments to be published via JCTLM DB | This reference measurement method was developed and validated by Roche Diagnostics GmbH in collaboration with the Institute of Laboratory Medicine, Hospital of the Ludwig-Maximilians University, and Labormedizinisches Zentrum |
| Analyte Category Name | Drugs |
| Measurement principle/technique | Isotope dilution mass spectrometry |