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Details : C17RMP4 - CDC equilibrium dialysis ID LC-MS/MS reference measurement procedure for free thyroxine in human serum
| Type (acronym) | rmp |
|---|---|
| Type | reference measurement procedure |
| Unique Nomination Number | C17RMP4 |
| Analyte Name | free thyroxine |
| IUPAC IFCC Number | free thyroxine |
| Method capable of Traceability of Analyte to SI or Defined Procedure | Traceable to SI |
| Name | CDC equilibrium dialysis ID LC-MS/MS reference measurement procedure for free thyroxine in human serum |
| Organization that developed Validated Method | Centers for Control and Prevention,CDC |
| Measurement Techniques Used | Equilibrium dialysis isotope dilution-liquid chromatography tandem mass spectrometry (ID LC-MS/MS) |
| Comments 1 | Calibrated with IRMM 468 |
| Quantity | Amount-of-substance concentration
|
| From (0) | 1.29 |
| To (0) | 258 |
| Unit (0) | pmol/L |
| From (1) | 7 |
| To (1) | 8.8 |
| Unit (1) | % |
| Level of Confidence (%) | 95 % |
| Peer Reviewed Publication | Development of an equilibrium dialysis ID-UPLC-MS/MS candidate reference measurement procedure for free thyroxine in human serum, Zhang L. et al, Clinical Biochemistry 2023 116:42-51 |
| Analyte Category Name | Non-peptide hormones |
| Non-CCQM Key Comparison Report | See reference cited for comparability assessment study |
| Measurement principle/technique | Isotope dilution mass spectrometry |