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Details : C18RM22 - Human DNA mixture in serum for noninvasive prenatal testing of Downsyndrome
| Type (acronym) | rm2 |
|---|---|
| Type | reference material |
| Unique Nomination Number | C18RM22 |
| Analyte Name | Human DNA |
| List I, II or III | List I |
| Basis for Traceability Claim | SI |
| Applicable Matrices | frozen bovine serum |
| Identifier Number | CRM 111-10-504 |
| Name | Human DNA mixture in serum for noninvasive prenatal testing of Downsyndrome |
| Certifying Organization | KRISS |
| Quantity | Mass fraction of Down syndrome DNA to total human DNA |
| From (0) | 0.096 |
| To (0) | 0.096 |
| Unit (0) | kg/kg |
| From (1) | 0.008 |
| To (1) | 0.008 |
| Unit (1) | kg/kg |
| Level of Confidence (%) | 0.95 |
| Reference to Commutability Study Publication | Commutability of the RM was assessed by comparing the certified value and fetal fractions measured following a routine NIPT protocol. The results are described in the certification report but not published yet. |
| Other Relevant Publications | Certification method: Anal. Chem. 2019, 91, 3936 -3943 |
| Recommended for Publication in the JCTLM List | Yes |
| Organization Acronym | KRISS |
| Organization Name | Korea Research Institute of Standards and Science |
| Organization Website | http://www.kriss.re.kr/ |
| Organization Country ISO Code | KR |
| Organization Country Name | Korea, Republic of |
| Analyte Category Name | Nucleic acids |