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Details : C3RMMP1 - CDC LC/MS/MS reference method for folates (5-methyltetrahydrofolic acid)
| Type (acronym) | rmp |
|---|---|
| Type | reference measurement procedure |
| Unique Nomination Number | C3RMMP1 |
| Analyte Name | 5-methyltetrahydrofolic acid |
| IUPAC IFCC Number | CAS68792-52-9 |
| Method capable of Traceability of Analyte to SI or Defined Procedure | SI |
| Applicable Matrices | human serum |
| Name | CDC LC/MS/MS reference method for folates (5-methyltetrahydrofolic acid) |
| Organization that developed Validated Method | CDC |
| Measurement Techniques Used | LC/MS/MS |
| Comments 1 | Isotope Dilution |
| Quantity | Amount-of-substance concentration |
| From (0) | 0.22 |
| To (0) | 220 |
| Unit (0) | nmol/L |
| Peer Reviewed Publication | Determination of folate vitamers in human serum by stable isotope dilution tandem mass spectrometry and comparison with radioassay and microbiologic assay, Pfeiffer C M et al., Clin. Chem., 2004, 50, 423-432 |
| Measurand Clearly Defined | yes |
| Review Team Name | vitamins |
| Analyte Category Name | Vitamins and micronutrients |
| Non-CCQM Key Comparison Report | SRM 1955 value assignment manuscript - Anal. Bioanal. Chem., 2006, 385, 612-622 |
| Measurement principle/technique | Liquid chromatography mass spectrometry |