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Details : C6RM14 - aspartate aminotransferase
| Type (acronym) | rm |
|---|---|
| Type | reference material |
| Unique Nomination Number | C6RM14 |
| Analyte Name | aspartate transaminase (AST) or aspartate aminotransferase (ASAT) |
| IUPAC IFCC Number | DNK05064 |
| List I or II | List I |
| Traceable to SI | Yes |
| Procedurally Defined by Procedure | IFCC reference procedure at 37 °C, Clin. Chem. Lab. Med., 2002, 40, 725-733 |
| Applicable Matrices | recombinant enzyme in albumin carrier matrix |
| Identifier Number | ERM-AD457/IFCC |
| Name | aspartate aminotransferase |
| Certifying Organization | IRMM |
| Mode Approach used for Value Assignment | Interlaboratory comparison using IFCC reference procedure at 37 °C |
| Issued by NMI with Certificate | no |
| Certificate from Other RM Provider | no |
| RM Listed in BIPM Key Comparison Database (KCDB) | no |
| Quantity | Catalytic activity concentration |
| From (0) | 1.74 |
| To (0) | 1.74 |
| Unit (0) | µkat/L |
| From (1) | 0.05 |
| To (1) | 0.05 |
| Unit (1) | µkat/L |
| Level of Confidence (%) | 95 % |
| Physical Form of RM Matrix | lyophilised |
| RM Fortified with Analyte or Naturally Incurred | fortified |
| Applicable Analyte Characteristics (e.g. Isoform, Free/Bound) | recombinant from E. Coli, cytosolic isoform originating from human liver |
| Expression of Uncertainty | in accordance with GUM |
| Justification of Reference Material Source | recombinant material from high purity showing commutability with human serum in IFCC preliminary studies |
| Are Intended Use and Instructions for Use Available | yes |
| Are Dates of Authorization and Revision Given | date of certificate validity given |
| Are Safety Precautions Listed | no safety precautions required |
| Validation Report Available | IFCC reference procedure at 37 °C |
| Other Relevant Publications | ERM-DA457/IFCC Certification Report |
| How to Obtain Certificate | http://www.irmm.jrc.be |
| Sustainable Source Available for the Material | no |
| Does RM Value Assignment Traceability Meet Requirements | Yes |
| Recommended for Publication in the JCTLM List | Yes |
| Review Team Name | Enzymes |
| Published CRM ISO Compliance | False |
| Organization Acronym | EU - JRC |
| Organization Name | European Commission - Joint Research Centre |
| Organization Website | https://crm.jrc.ec.europa.eu/ |
| Organization Country ISO Code | BE |
| Organization Country Name | Belgium |
| Analyte Category Name | Enzymes |