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Details : C8RMP1 - University of Ghent reference measurement procedure for free thyroxine in serum
| Type (acronym) | rmp |
|---|---|
| Type | reference measurement procedure |
| Unique Nomination Number | C8RMP1 |
| Analyte Name | free thyroxine |
| IUPAC IFCC Number | free thyroxine |
| Method capable of Traceability of Analyte to SI or Defined Procedure | defined procedure |
| Applicable Matrices | lyophilized, fresh, or frozen serum |
| Name | University of Ghent reference measurement procedure for free thyroxine in serum |
| Organization that developed Validated Method | University of Ghent |
| Measurement Techniques Used | equilibrium diaysis ID/LC/MS |
| Comments 1 | Equilibrium dialysis under well defined conditions followed by ID-LC-/tabdem MS measurement based on JCTLM NRMeth 11 |
| Comments 2 | Calibrated by JCTLM listed T4 certified reference material IRMM 468, accuracy control with DGKL-sera certified for total T4 and self-prepared IQC pools |
| Quantity | Amount-of-substance concentration |
| From (0) | 1.8 |
| To (0) | 80 |
| Unit (0) | pmol/L |
| From (1) | 6.9 |
| To (1) | 6.9 |
| Unit (1) | % |
| Level of Confidence (%) | 95% |
| Peer Reviewed Publication | Clin. Chem. Lab. Med., 2011, 49(8), 1275 - 1281 |
| Analyte Category Name | Non-peptide hormones |
| Measurement principle/technique | Isotope dilution mass spectrometry |