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Details : NRMeth 11 - University of Ghent reference measurement procedure for total thyroxine
| Type (acronym) | rmp |
|---|---|
| Type | reference measurement procedure |
| Unique Nomination Number | NRMeth 11 |
| Analyte Name | total thyroxine |
| IUPAC IFCC Number | total thyroxine |
| Method capable of Traceability of Analyte to SI or Defined Procedure | SI |
| Applicable Matrices | lyophilized, fresh, or frozen human serum |
| Name | University of Ghent reference measurement procedure for total thyroxine |
| Organization that developed Validated Method | University of Ghent |
| Measurement Techniques Used | ID/GC/MS and ID/LC/MS/MS |
| Comments 1 | N,O-diheptafluorobutyryl methyl derivative (for GC/MS) |
| Comments 2 | Calibrated with Aldrich or Acros high purity thyroxine; accuracy control with Network sera |
| Quantity | Amount-of-substance concentration |
| From (0) | 35 |
| To (0) | 300 |
| Unit (0) | nmol/l |
| From (1) | 1.75 |
| To (1) | 3.5 |
| Unit (1) | % |
| Level of Confidence (%) | 95% |
| Peer Reviewed Publication | Biol. Mass Spectrom., 1994, 23, 475-482 J. Mass Spectrom., 1998, 33, 1032 Eur. J. Clin. Chem. Clin. Biochem., 1996, 34, 853-860 Rapid Commun. Mass Spectrom., 1998, 12, 1099-1103 |
| Review Team Name | non-peptide hormones |
| Analyte Category Name | Non-peptide hormones |
| Measurement principle/technique | Isotope dilution mass spectrometry |