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Details : NRMeth 46 - DGKC reference method for serum cholesterol

Type (acronym)rmp
Typereference measurement procedure
Unique Nomination NumberNRMeth 46
Analyte Nametotal cholesterol
IUPAC IFCC NumberCAS57-88-5
Method capable of Traceability of Analyte to SI or Defined ProcedureSI
Applicable Matriceslyophilized, fresh, or frozen human serum or plasma
NameDGKC reference method for serum cholesterol
Organization that developed Validated MethodGerman Society of Clinical Chemistry (DGKC)
Measurement Techniques UsedID/GC/MS
Comments 1trimethylsilyl derative
Comments 2Calibrate with SRM 911b, high purity cholesterol
QuantityAmount-of-substance concentration
From (0)2
To (0)10
Unit (0)mmol/l
From (1)0.5
To (1)1.5
Unit (1)%
Level of Confidence (%)95%
Peer Reviewed PublicationSiekmann et al., Z. anal. Chem., 1976, 279, 145-146
Review Team Namemetabolites and substrates
Analyte Category NameMetabolites and substrates
CCQM Key Comparison ReportMetrologia, 2004, 39, Tech. Suppl., 08001
CCQM Key Comparison Report Hyperlinkhttp://stacks.iop.org/met/39/08001
Measurement principle/techniqueIsotope dilution mass spectrometry