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Details : NRMeth 50 - DGKC reference method for uric acid in serum or plasma

Type (acronym)rmp
Typereference measurement procedure
Unique Nomination NumberNRMeth 50
Analyte Nameuric acid
IUPAC IFCC NumberCAS69-93-2
Method capable of Traceability of Analyte to SI or Defined ProcedureSI
Applicable Matriceslyophilized, fresh, or frozen human serum or plasma
NameDGKC reference method for uric acid in serum or plasma
Organization that developed Validated MethodGerman Society of Clinical Chemistry (DGKC)
Measurement Techniques UsedID/GC/MS
Comments 1Tert-butyl-di-methyl-silyl derivative
Comments 2Calibrate with SRM 913, high purity uric acid
QuantityAmount-of-substance concentration
From (0)100
To (0)700
Unit (0)µmol/l
From (1)0.5
To (1)1.5
Unit (1)%
Level of Confidence (%)95%
Peer Reviewed PublicationSiekmann et al., J. Clin. Chem. Clin. Biochem., 1985, 23, 129-135
Review Team Namemetabolites and substrates
Analyte Category NameMetabolites and substrates
Non-CCQM Key Comparison ReportBenchmarked with PTB reference method for uric acid in serum or plasma
Non-CCQM Key Comparison Report Hyperlink
Non-CCQM Key Comparison Reportfor information, contact lothar.siekmann@ukb.uni-bonn.de
Non-CCQM Key Comparison Report Hyperlink
Measurement principle/techniqueIsotope dilution mass spectrometry