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Details : NRMeth 81 - NIST reference method for serum cholesterol

Type (acronym)rmp
Typereference measurement procedure
Unique Nomination NumberNRMeth 81
Analyte Nametotal cholesterol
IUPAC IFCC NumberCAS57-88-5
Method capable of Traceability of Analyte to SI or Defined ProcedureSI
Applicable Matriceslyophilized, fresh, or frozen human serum
NameNIST reference method for serum cholesterol
Organization that developed Validated MethodNIST
Measurement Techniques UsedID/GC/MS
Comments 1trimethylsilyl derative
Comments 2Calibrate with SRM 911b, Cholesterol
QuantityAmount-of-substance concentration
From (0)2
To (0)10
Unit (0)mmol/l
From (1)0.5
To (1)1
Unit (1)%
Level of Confidence (%)95%
Peer Reviewed PublicationAnal. Chem., 1989, 61, 1718-1723
Review Team Namemetabolites and substrates
Analyte Category NameMetabolites and substrates
CCQM Key Comparison ReportMetrologia, 2004, 39, Tech. Suppl., 08001
CCQM Key Comparison Report Hyperlinkhttp://stacks.iop.org/met/39/08001
Non-CCQM Key Comparison ReportClin. Chem., 1990, 36, 370-375
Non-CCQM Key Comparison Report Hyperlink
Measurement principle/techniqueIsotope dilution mass spectrometry