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Details : NRMeth 89 - NIST LC/MS/MS reference method for serum homocysteine

Type (acronym)rmp
Typereference measurement procedure
Unique Nomination NumberNRMeth 89
Analyte Namehomocysteine
IUPAC IFCC NumberCAS454-29-5
Method capable of Traceability of Analyte to SI or Defined ProcedureSI
Applicable Matriceslyophilized, fresh, or frozen human serum
NameNIST LC/MS/MS reference method for serum homocysteine
Organization that developed Validated MethodNIST
Measurement Techniques UsedID/LC/MS/MS
Comments 1no derivative
Comments 2Calibrate with commercial material characterized at NIST
QuantityAmount-of-substance concentration
From (0)7
To (0)21
Unit (0)µmol/l
From (1)1.5
To (1)3
Unit (1)%
Level of Confidence (%)95%
Peer Reviewed PublicationAnal. Chem., 2003, 75, 4631-4638
Review Team Namemetabolites and substrates
Analyte Category NameMetabolites and substrates
Non-CCQM Key Comparison ReportSee reference cited for comparability assessment study
Non-CCQM Key Comparison Report Hyperlink
Measurement principle/techniqueIsotope dilution mass spectrometry